WOMEN’S HEALTH • FERTILITY CARE
Recurrent Implantation Failure
Understand the factors that may affect embryo implantation and how a detailed review can help guide the next fertility treatment step.
What is recurrent implantation failure?
Implantation failure occurs when an embryo does not implant after embryo transfer. When implantation does not occur repeatedly, reviewing embryo, uterine and other fertility factors may help guide future treatment.
What can affect embryo implantation?
Pregnancy loss may result from different factors, sometimes occurring together.

Embryo chromosomal abnormalities

Uterine abnormalities

Endometrial factors

Hormonal factors

Embryo development

Age-related fertility factors
What may indicate recurrent implantation failure?
There may be no specific physical symptoms.

Repeated unsuccessful embryo transfers

Negative pregnancy tests after transfer

Previous implantation failure

Uterine abnormalities

Endometrial concerns

Embryo-related concerns
How is recurrent implantation failure evaluated?
A review of previous treatment can help identify areas that may need attention.
1. Previous Cycle Review
We assess previous IVF cycles, embryos and transfer outcomes.
2. Embryo Assessment
Embryo development and, when appropriate, genetic factors may be reviewed.
3. Uterine Assessment
The uterus and endometrial lining may be evaluated
4. Medical & Hormonal Review
Relevant hormonal, metabolic and other factors may be assessed.
Treatment Options for Recurrent Implantation Failure
Treatment is based on findings from the individual evaluation
Uterine Evaluation
Structural abnormalities may be identified and treated.
Endometrial Management
The uterine lining and transfer timing may be reviewed.
Embryo Assessment
Embryo development and genetic testing may be considered where appropriate.
Personalized Embryo Transfer
Transfer planning may be adjusted based on individual findings.
IVF Treatment Planning
Future cycles may be modified based on previous treatment outcomes.
Frequently Aksed Questions?
1. Why does an embryo fail to implant?
Possible factors include embryo quality, uterine conditions and endometrial factors.
2. Does implantation failure mean IVF will not work?
No. Further evaluation may identify factors that can be addressed.
3. Can the uterus be tested after implantation failure?
Yes. Uterine and endometrial assessment may be recommended.
4. Can embryo genetics affect implantation?
Chromosomal abnormalities in embryos can affect implantation and pregnancy development.
5. Can IVF be repeated after implantation failure?
Yes. The treatment plan may be reviewed and adjusted before another cycle.
6. Is there one test that can identify the cause?
No. Evaluation usually involves reviewing several possible factors.
A failed transfer does not have to mean the end of your fertility journey
Review your previous treatment and understand your next options